by Prof. Dr. med. Wilhelm Schulte-Mattler
14.09.2017, 17:00 h, TF, Aquarium
Physiologie peripherer Nerven aus Sicht der Signalverarbeitung
To transmit information, peripheral nerve fibers locally change their electrical membrane properties. The changed regions move along the fibers causing traveling electrical fields, causing changes in voltage over time that depend both on where the voltage is recorded and on the nerve’s properties. Things are complicated by the nerves being composed of many thousands of fibers.
A simple model that explains these voltage changes, namely the signals that are recorded from actively transmitting nerves, will be presented. These signals provide information about the nerve’s function. Both, the influence of the recording conditions and the influence of various nerve disorders on the recorded waveforms will be presented. The usefulness of simple measures, such as amplitude and duration, is established. More advanced signal analysis indeed provides more information about peripheral nerve disorders.
Wilhelm Schulte-Mattler studied Mathematics and Physics, followed by Medicine. He graduated at the University of Würzburg in 1988. His thesis was on Quantification of recruitment in needle-EMG. He specialized in Neurology in 1993. After heading Clinical Neurophysiology in the Dept. of Neurology, University of Halle-Wittenberg; since the year 2000, he is head of Clinical Neurophysiology in the Dept. of Neurology, University of Regensburg. A significant part of his work is on waveform analysis in clinical neurophysiology, particularly in electromyography and in electroneurography.