Project B6

Multimodal Mapping of Nerve Pathology with Magnetoelectric Sensors

The objective of project B6 is the non-invasive mapping of nerve function and dysfunction (pathology) by a combination of magnetoelectric (ME) sensor sampling with ultrasound or magnetic resonance (MR) imaging. In step 1, we will establish the experimental set-up with the measurement and analysis pipeline using a phantom. In step 2, we will adapt these to in vivo conditions (healthy human nerve). Finally, in step 3, we will examine patient cohorts with different types of nerve pathology and assess added value of the novel multimodal nerve mapping in comparison to established electrical nerve conduction studies.

 

Helmut Laufs
PhD, PD Dr. med.
Lead of project B6, IRTG
Gerhard Schmidt
Prof. Dr.-Ing.
Lead of projects B2, B6, and Z2
Eric Elzenheimer
M. Sc.
Doctoral researcher
Franziska Weitkamp
Doctoral student
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Role within the Collaborative Research Centre

Close cooperation is planned with the following partners:

 Z1, A3: This project is closely interlinked with the ME sensor projects, especially those that operate in resonance and those where the resonance frequency can be adjusted.
B1: B6 will benefit from B1adapting system front-ends and small sensor arrays to the requirements of B6. In turn, we will communicate test results back to B1 to facilitate the development of suitable measurement systems after transfer of mature sub-systems to Z2.
B2, B6: The project will use the same real-time framework as projects B2 and B6. Thus, all extensions made in either one of the projects will benefit the other and immediately speed up development.
B3: We will share data with project B3 for the advancement of inverse solution techniques.
B5: All patient management and data acquisition will be shared with project B5, via which a neurophysiologist/technician will be employed. Patients will be recruited from the same site (Department of Neurology, UKSH Kiel).
Z2: We will share work with the other projects that are producing or extending phantoms.


Project B6 will participate in the focus group F3 “Biomagnetic Signal Analysis”.

Project-related Publications

E. Elzenheimer, F. Weitkamp, H. Laufs, T. Sander-Thömmes, G. Schmidt: Magnetoneurografie eines elektrisch stimulierten Armnervs, Biosignale Workshop, März 2018, Erfurt, Germany

F. Weitkamp, E. Elzenheimer, W. Schulte-Mattler, G. Schmidt, H. Laufs: Multimodal Mapping of Nerve Pathology with a Multichannel Approach, DGKN, März 2018, Berlin, Germany

C. Bald, E. Elzenheimer, J. Reermann, T. Sander-Thömmes, G. Schmidt: Amplitudenverlauf des Herzmagnetfeldes als Funktion des Abstandes, Biosignale Workshop, März 2018, Erfurt, Germany

Financial Support

The Collaborative Research Center 1261 is funded by the German Research Foundation (DFG).

SFB1261 Microsite

Click here to visit our Microsite with information for students, teachers and the public (German and English version available).

Upcoming Events

Recent Publications

J. Reermann, P. Durdaut, S. Salzer, T. Demming, A. Piorra, E. Quandt, N. Frey, M. Höft, and G. Schmidt: Evaluation of Magnetoelectric Sensor Systems for Cardiological Applications, Measurement (Elsevier), ISSN 0263-2241, 2017, https://doi.org/10.1016/j.measurement.2017.09.047

S. B. Hrkac, C. T. Koops, M. Abes, C. Krywka, M. Müller, M. Burghammer, M. Sztucki, T. Dane, Kaps, Y. K. Mishra,R. Adelung, J. Schmalz, M. Gerken, E. Lage, C. Kirchhof, E. Quandt, O. M. Magnussen, and B. M. Murphy: Tunable Strain in Magnetoelectric ZnO Microrod Composite Interfaces; ACS Appl. Mater. Interfaces, 2017, 9 (30), pp 25571–25577; DOI: 10.1021/acsami.6b15598

 

Contact

sfb1261@tf.uni-kiel.de

Chairman:

Prof. Dr. Eckhard Quandt

Kiel University
Institute for Materials Science

 

Interner Server

 

CAU

Christian-Albrechts-Universität zu Kiel (CAU)

Christ.-Albrechts-Platz 4
D-24118 Kiel

UKSH

University Hospital Schleswig-Holstein, Campus Kiel (UKSH)

Arnold-Heller-Straße 3
D-24105 Kiel

ISIT

Fraunhofer Institute for Silicon Technology, Itzehoe (ISIT)

Fraunhoferstrasse 1
D-25524 Itzehoe  

IPN

IPN - Leibniz-Institut für die Pädagogik der Naturwissenschaften und Mathematik an der Universität Kiel

Olshausenstraße 62 
D-24118 Kiel

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